By Hans-Peter Lipp
Containing the newest findings at the toxicity of a variety of chemotherapeutic brokers, this up to date reference deals specialist analyses at the pharmacokinetic-pharmacodynamic and pharmacokinetic-toxicodynamic relationships of anticancer compounds. Anticancer Drug Toxicity ·explores healing drug tracking (TDM) as a mode of maximizing the efficacy, and minimizing the hazards, of chemotherapy ·presents an enormous volume of scientific pharmacokinetic information on cytostatic medicines ·offers a finished class of toxicity styles linked to using cytotoxic medicines ·analyzes the pharmacokinetics of alkylating brokers, platinum compounds, anthracyclines, antimetabolites, semisynthetic podophyllotoxin- and camptothecin derivatives, mitotic inhibitors, and different cytotoxic brokers ·highlights the pharmacogenetics of 6-mercaptopurine and its scientific importance ·explicates toxicity on the subject of the lungs, kidneys, center, and gonads ·examines issues brought on by asparaginase arrangements ·reviews different types of secondary malignancy resembling leukemias, ovarian melanoma, testicular melanoma, breast melanoma, secondary strong neoplasias, and Hodgkin's ailment ·clarifies the knowledge of toxicity as a vital aspect in supportive administration of melanoma remedy ·and extra! An drastically sensible advisor for daily scientific perform, in addition to a resource of suggestion for extra examine within the box, Anticancer Drug Toxicity is a useful reference for scientific and clinical oncologists; clinic, commercial, and scientific pharmacologists and pharmacists; toxicologists; pharmaceutical chemists; radiologists; and graduate and clinical institution scholars in those disciplines.
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Extra info for Anticancer Drug Toxicity: Prevention, Management, and Clinical Pharmacokinetics
The word “pepper” is derived from the Sanskrit “Pippali”, meaning long pepper. Black pepper (“Maricha” in Sanskrit) is known by other names in the local dialect as “Milagu” (Tamil), “Kuru Mulagu” (Malayalam), “Miriyam” (Telugu), “Miriya Konu” (Konkani), and “Kari Menasu” (Kannada). The fruit, also known as peppercorn, is dark red when fully mature, and a small black wrinkled drupe 5 mm in diameter when dried. Black pepper is produced from the green unripe berries of the pepper plant by briefly cooking in hot water.
CORIANDER Coriandrum sativum L. Apiaceae (Umbelliferae) (coriander, also known as cilantro, cilantrillo, Arab parsley, Chinese parsley, Mexican parsley, Dhania and Yuen sai), is native to southwestern Asia and regions west to north Africa. 20 It is an annual herb commonly used in Middle Eastern, Mediterranean, Indian, Latin American, African and Southeast Asian cuisine. Coriander leaves are referred to as cilantro (United States and Canada, from the Spanish name for the plant), dhania (Indian subcontinent, and increasingly in Britain), kindza (in Georgia), Chinese parsley or Mexican parsley.
Emamghoreishi M, Khasaki M and Aazam MF (2005). Coriandrum sativum: Evaluation of its anxiolytic effect in the elevated plus-maze. J. Ethnopharmacol. 96(3): 365–370. 23. Reuter J, Huyke C, Casetti F, Theek C, Frank U, Augustin M and Schempp C (2008) Anti-inflammatory potential of a lipolotion containing coriander oil in the ultraviolet erythema test. J. Dtsch. Dermatol. Ges. 6(10): 847–851. qxd 22 4/24/2009 3:59 PM Page 22 A. B. Kunnumakkara et al . 24. Gray AM and Flatt PR (1999). Insulin-releasing and insulin-like activity of the traditional anti-diabetic plant Coriandrum sativum (coriander).