Download Analytical Determination of Nicotine and Related Compounds by J.W. Gorrod, P. Jacob III PDF

By J.W. Gorrod, P. Jacob III

ISBN-10: 0444500952

ISBN-13: 9780444500953

This booklet offers for the 1st time a unmarried finished resource of data at the analytical chemistry of nicotine and comparable alkaloids. The editors have introduced jointly scientists from academia and the tobacco to explain the cutting-edge of the chemistry and analytical equipment for size of nicotine. either the scope and element of the booklet are striking. Chapters describe the background, pharmacology and toxicology of nicotine, the biosynthesis of nicotine and different alkaloids within the tobacco plant, the overall chemistry of nicotine and the analytical methodologies which were used to degree nicotine and comparable alkaloids in organic specimens, in tobacco and pharmaceutical items and in tobacco smoke. there's additionally a complete evaluation of the chemistry and toxicology of nicotine-derived nitrosamines, an enormous category of tobacco cancer causing agents.

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Additional resources for Analytical Determination of Nicotine and Related Compounds and their Metabolites

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Leaf cuttings (Blattstecklinge) of N. rustica, which had developed roots in culture, were subjected to repeated excision of portions of their root tissue, and their nicotine contents were compared to those of uninjured rooted cuttings of similar age. Root tissue that had been removed was replaced by active growth. The lamina of rooted cuttings, whose roots had been cut four times over a period of nearly six months, contained nearly three times as much nicotine as did lamina of undisturbed rooted cuttings.

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Physiology and biochemistry of tobacco alkaloids. Recent Adv. Tob. , 1981: 7; 75-106. 38 Biosynthesis of Nicotine and Related Compounds 17 Tiburcio AF, Galston AW. Arginine decarboxylase as the source of putrescine for tobacco alkaloids. Phytochemistry, 1986: 25; 107-110. 18 Burtin D, Michael AJ. Overexpression of arginine decarboxylase in transgenic plants. Biochem. , 1997: 325; 331-337. 19 Saunders JW, Bush LP. Nicotine biosynthetic enzyme activities in Nicotiana tabacum L. genotypes with different alkaloid levels.

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