Download Acute Drug Abuse Emergencies. A Treatment Manual by M.D. Peter G. Bourne PDF

By M.D. Peter G. Bourne

ISBN-10: 0121195651

ISBN-13: 9780121195656

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Pharmacology and Use of M e t h a d o n e M e t h a d o n e is an opioid drug which, like h e r o i n and m o r p h i n e , has analgesic, sedative, and euphorigenic p r o p e r t i e s . Similarly, tolerance and physical d e p e n d e n c e develop with prolonged or r e p e a t e d use. Overdosage causes d e a t h b y respiratory depression in t h e n o n t o l e r a n t individual or when tolerance is o v e r c o m e in t h e already physically d e p e n d e n t individual. M e t h a d o n e m a y be t a k e n by m o u t h , injected either s u b c u t a n e o u s l y or intraveneously, or inhaled.

2. T h e presence of h y p o g l y c e m i a . 3. Unmasking of a m u l t i p l e overdose: a m p h e t a m i n e s , anticholin­ ergics, and p s y c h o t o m i m e t i c s m a y p r o d u c e agitation. 4 . Unmasking of an abstinence s y n d r o m e : delirium t r e m e n s , bar­ b i t u r a t e w i t h d r a w a l , a n d h e r o i n w i t h d r a w a l are c a n d i d a t e s . 2. DILATED PUPILS T h e pupils m a y be dilated in t h e setting of severe overdose w i t h h y p o x i a and cerebral anoxia, or if t h e p a t i e n t has t a k e n o t h e r drugs.

Int J Addict, 2:53, 1967. D. Arch Intern Med, 122:122,1968. Neurology, 21:453,1971. X4M^, 206:1255, 1968. ; and Ramsey, W. Clin Res, 18:695,1970. AmerJMed, 45:555,1968. THE TREATMENT OF ACUTE HEROIN TOXICITY H e r b e r t D . Kleber I. Introduction II. Diagnosis III. General Management A. Immediate Steps B. Maintenance of Respiration C. Maintenance of Circulation D. Narcotic Antagonists E. Other Measures IV. FollowupCare V. Conclusion VI. Etiologic Factors 33 ^5 35 35 36 37 38 39 39 39 I. I n t r o d u c t i o n In t h e past t h e t r e a t m e n t of a c u t e h e r o i n t o x i c i t y ( m o r e c o m m o n l y k n o w n as heroin overdose or j u s t O D ) , was mainly confined t o t h e emergency r o o m s of large city hospitals.

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