By M.D. Peter G. Bourne
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The danger research and important keep watch over element (HACCP) method has now develop into commonly approved because the key protection administration method for the meals around the world. when there are various courses on its ideas and techniques of implementation, there's particularly little at the adventure of these who've really carried out HACCP structures in perform and what could be learnt from that have.
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Extra info for Acute Drug Abuse Emergencies. A Treatment Manual
Pharmacology and Use of M e t h a d o n e M e t h a d o n e is an opioid drug which, like h e r o i n and m o r p h i n e , has analgesic, sedative, and euphorigenic p r o p e r t i e s . Similarly, tolerance and physical d e p e n d e n c e develop with prolonged or r e p e a t e d use. Overdosage causes d e a t h b y respiratory depression in t h e n o n t o l e r a n t individual or when tolerance is o v e r c o m e in t h e already physically d e p e n d e n t individual. M e t h a d o n e m a y be t a k e n by m o u t h , injected either s u b c u t a n e o u s l y or intraveneously, or inhaled.
2. T h e presence of h y p o g l y c e m i a . 3. Unmasking of a m u l t i p l e overdose: a m p h e t a m i n e s , anticholin ergics, and p s y c h o t o m i m e t i c s m a y p r o d u c e agitation. 4 . Unmasking of an abstinence s y n d r o m e : delirium t r e m e n s , bar b i t u r a t e w i t h d r a w a l , a n d h e r o i n w i t h d r a w a l are c a n d i d a t e s . 2. DILATED PUPILS T h e pupils m a y be dilated in t h e setting of severe overdose w i t h h y p o x i a and cerebral anoxia, or if t h e p a t i e n t has t a k e n o t h e r drugs.
Int J Addict, 2:53, 1967. D. Arch Intern Med, 122:122,1968. Neurology, 21:453,1971. X4M^, 206:1255, 1968. ; and Ramsey, W. Clin Res, 18:695,1970. AmerJMed, 45:555,1968. THE TREATMENT OF ACUTE HEROIN TOXICITY H e r b e r t D . Kleber I. Introduction II. Diagnosis III. General Management A. Immediate Steps B. Maintenance of Respiration C. Maintenance of Circulation D. Narcotic Antagonists E. Other Measures IV. FollowupCare V. Conclusion VI. Etiologic Factors 33 ^5 35 35 36 37 38 39 39 39 I. I n t r o d u c t i o n In t h e past t h e t r e a t m e n t of a c u t e h e r o i n t o x i c i t y ( m o r e c o m m o n l y k n o w n as heroin overdose or j u s t O D ) , was mainly confined t o t h e emergency r o o m s of large city hospitals.